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­¡Journal: Cold Spring Harbor Laboratory, bioRxiv, THE PREPRINT SERVER FOR BIOLOGY
Title: Nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants
https://www.biorxiv.org/content/10.1101/2021.10.25.465714v1

­¢Journal: Communications Biology.
DOI : 10.1038/s42003-022-03630-3
Title : A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron.
https://rdcu.be/cQ5Aq

¢£PRTIMESµ­»ö(2022ǯ10·î15Æü10:00)¢£
https://prtimes.jp/main/html/rd/p/000000002.000104790.html

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https://www.cognano.co.jp/2022/07/15/a-panel-of-nanobodies-recognizing-conserved-hidden-clefts-of-all-sars-cov-2-spike-variants-including-omicron/

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category immunogen(¹³¸¶¡Ë target molecule(ɸŪʬ»Ò¡Ë
Albumin HSA Human serum albumin
LSA Lyama serum albumin
Chromatin HP1 Chromatin protein
Cytokine IL6 Human interleukin-6
TNFa Human tumor necrosis factor alpha
GPCR CXCR1 Chemokine receptor
CXCR2 Chemokine receptor
CXCR4 Chemokine receptor
GPRC5b Orphan receptor
GPRC5c Orphan receptor
CaSR Calcium sensing receptor
CCR5 Chemokine receptor
b2AR Adrenaline receptor
OPRd1 Opioid receptor
OPRk1 Opioid receptor
OPRm1 Opioid receptor
HTR1B Histamine receptor
HTR2B Histamine receptor
GMR1 Glutamine receptor
GMR5 Glutamine receptor
CHRNA1 Cholinergic Receptor Nicotinic Alpha I
CHR3M acetylcholine receptor
CHR4M acetylcholine receptor
b1AR Adrenaline receptor
Immunoglbulin hIgG Human IgG
bIgG Bovine IgG
Membrane protein hTsp1 Human Tetraspanin 1
hTsp4 Human Tetraspanin 4
hTsp8 Human Tetraspanin 8
Receptor Her2 EGF receptor 2
hOX40 Human OX40
fOX40 Feline OX40
hCD4 Human CD4
Sugar MUC1-Tn Tn-Type glycan
MUC1-STn Sialyl Tn-type glycan
Virus HIV Env HIV Envelope protein
Ebora Env Ebora Envelope protein
FIV vaccine Feline Immunodeficiency virus
RV vaccine Rabies virus

designing & optimization VHH-applied CAR-T vector

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